RVS physicians have served as principal investigators in many clinical trials over the past 30 years and continue their ongoing commitment to improving the quality and safety of retinal treatments. We strongly believe that our patients and community should have access to cutting-edge medical care through offering the option of clinical research. We partner with the National Institute of Health, the National Eye Institute, and some of the nation's top pharmaceutical companies in our quest for improving patient care and quality of life. All of our trials are sponsored; so eligible participants will not incur additional costs. Contact us at (315)-445-8166 if you are interested in finding out more information about possible participation in our clinical research.

 

Active Clinical Trials:

Diabetic Retinopathy
Diabetic Retinopathy Clinical Research Network – National Institute of Health
Protocol T - A Comparative Effectiveness Study of Intravitreal Aflibercept, Bevacizumab and Ranibizumab for Diabetic Macular Edema

 

Age Related Macular Degeneration
Regeneron VEGF Trap – Open label Phase III Study of the long term safety and effectiveness of repeated doses of Intravitreal VEGF Trap in subjects with Neovascular AMD


Closed Clinical Trials:

Macular Degeneration
Regeneron VEGF Trap 0605 – Randomized Double Masked Controlled Phase III Study of the Efficacy, Safety, and Tolerability of Repeated Doses of Intravitreal VEGF Trap in Subjects with Neovascular AMD

 

Novartis AG
VAM Study – Phase 3 Safety and Efficacy Study for Visudyne for Age Related Macular Degeneration
VERITAS – A Safety and Efficacy Study Comparing the Combination Treatments of Verteporfin Therapy Plus One of Two Different Doses of Intravitreal Triamcinolone Acetonide and the Verteporfin Therapy Plus Intravitreal Pegaptanib

Genentech – Phase 3b Safety Study for Ranibizumab for Age Related Macular (SAILOR)

Allergan – SIRIUS siRNA for Age Related Macular Degeneration

 

Retinal Vein Occlusion
Regeneron VEGF Trap – Randomized Double Masked Controlled Phase III Study of the Efficacy, Safety, and Tolerability of Repeated Doses of Intravitreal VEGF Trap in Subjects with Branch Vein Occlusions.

 

National Institute of Health – Standard Care vs. Corticosteroid for Retinal Vein Occlusion (SCORE) Study

 

Diabetic Retinopathy
Diabetic Retinopathy Clinical Research Network – National Institute of Health
Protocol A – A pilot study of laser photocoagulation for DME
Protocol B – A randomized trial comparing IVT and laser for DME
Protocol C – Temporal variation in OCT of retinal thickening measurements in DME
Protocol D – Evaluation of vitrectomy for ME
Protocol E – Pilot study of peribulbar triamcinolone acetonide
Protocol F – Observational study of the development of DME following scatter laser Photocoagulation
Protocol G – Subclinical DME study
Protocol K – Course of response to focal photocoagulation for DME
Protocol I – Laser-Ranibizumab-Triamcinolone for DME
Protocol J – Laser-Ranibizumab-Triamcinolone for DME + PRP
Protocol O – Comparison of TD & SD OCT
Protocol P – Cataract Surgery with Center-Involved DME
Protocol N – Intravitreal Ranibizumab for Vitreous Hge
Protocol R – Phase II non-Central DME NSAID
Protocol S – Prompt panretinal photocoagulation versus intravitreal Ranibizumab with deferred panretinal photocoagulation for PDR

 

Bristol-Myers-Squibb – Pilot Study of Irbesartain in the Hypertensive Type II Diabetic


 

Retinopathy of Prematurity
National Institute of Health
Cryotherapy for Retinopathy of Prematurity Study (CRYO-ROP)
Early Treatment for ROP (ETROP)

 

Vitreous Hemorrhage
ISTA Pharmaceuticals – Phase 3 Safety and Efficacy Study of Vitrase for Vitreous Hemorrhage

 

Other
United Biosource – VFQ Validation Study

 

Locations & Directions

 

Syracuse

 

Watertown

 

Binghamton

 

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